Dr. Veronica Catanese's laboratory is engaged in investigation of the pathogenesis of HIV protease-inhibitor associated lipodystrophy and hyperlipidemia using both molecular, biological and clinical/translational approaches. She and her group also work on dissecting the pathways signaling the hypertrophic vs. sclerotic phenotypes in mesangial cells, characterizing and isolating an IGF-dependent BP4 protease, and defining the mechanism by which IGF-I promotes TGF-beta activation in the kidney.