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Notes:
Results of Buspirone
Addition
- Of the 22 patients
taking SSRIs, 60% showed improvement with buspirone addition.
- Six patients
showed complete remission of their depressive symptoms and seven
patients showed partial remission.
- Of the eight patients
taking clomipramine, 63% showed improvement with buspirone addition.
- Three patients
showed complete remission of their depressive symptoms and two patients
showed partial remission.
- Of 14 responders
available for 6-month follow-up, 11 patients were symptom-free and three
patients were mildly ill.
- No serious side
effects were observed.
- The study supports
previous findings that depressed patients refractory to treatment with
SSRIs or such serotonergic agents as clomipramine can benefit from the
addition of buspirone to their antidepressant treatment.
Dimitriou, poster
presentation, 1996
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