Daniel Meruelo Ph.D.
Professor / Director Gene Therapy Center
Department of Pathology (Experimental)
Gene therapy and other approaches to detect and eradicate cancer.
Research Summary
Our group is involved in the development of gene therapy vectors that can target and eradicate tumor cells in vivo, whether they be localized or spread throughout the body. We utilize state of the art approaches to achieve this goal, including in vivo imaging.
Also we are engaged in studies of the high affinity laminin receptor, understanding its role in cancer, and its structure.
Other efforts in the lab are directed at discovering novel therapeutic agents for viral diseases and neurological diseases such as Alzheimers.
Related Documents
Systemic tumor targeting and killing by Sindbis viral vectors
Using Sindbis Viral Vectors for Specific Detection and Suppression of Advanced
Identification of Amino Acids of Sindbis Virus E2 Protein
Tumor-Specific In Vivo Transfection with HSV-1
Restricted tissue tropism and acquired resistance
Cell-specific targeting of Sindbis virus vectors
Related Images
Model for cloning the human homologue of the ecotropic retrovirus receptor and identifying the critical amino acids involved in ecotropic retrovirus binding. Such work allows for developing novel, safer vectors for direct in vivo gene therapy in humans.
Research Information
Research Interests
Gene Therapy, Alzheimer's research
Research Keywords
gene therapy, genetics, genomics, retroviruses, immunotherapy, acquired immunodeficiency syndrome (AIDS),
