January 8, 2001, the NIH issued a reminder of the format requirements for grant applications. In addition to the specific format instructions already available in the various grant application packages, such as the PHS 398, PHS 416, Phase I SBIR and STTR, and Phase II SBIR and STTR instructions (available at http://grants.nih.gov ), and the email address for general, application-related questions, the NIH has also created an email address specifically for formatting questions and a site to address such questions (format@mail.nih.gov, grantsinfor@nih.gov and http://www.format.nih.gov, respectively). Our office would also like to remind you that already formatted PDF and Excel files with Instructions which include Printing Tips and Help with using Adobe and Excel are available at our web site (see the Application Tools tab). This is particularly important, as the NIH has stated in this Notice that:

Applications that do not comply with the specifications for type size, page limits, or margins will be returned to the institution without review. These applications cannot be submitted in a corrected version until the next receipt cycle.

http://grants/nih/gov/grants/guide/notice-files/NOT-OD-01-012.html